Nestled in the heart of the Mediterranean, the port of Barcelona is a vibrant gateway to sun-soaked adventures and cultural wonders. This bustling hub offers holidaymakers an enticing blend of historic charm and modern allure, with its iconic architecture, lively markets, and tantalizing cuisine. As you embark on a cruise from this dynamic city, prepare to be whisked away to enchanting destinations like the French Riviera, the Amalfi Coast, and the Greek Isles. Each stop promises its own unique blend of history, beauty, and local flavour. Whether you're exploring ancient ruins, lounging on pristine beaches, or savouring local delicacies, the Mediterranean cruise experience is nothing short of magical. Returning to Barcelona, you'll find the city's energy infectious, inviting you to explore its vibrant neighbourhoods and indulge in its rich cultural tapestry. A cruise from Barcelona is more than a journey; it's a Mediterranean dream come true.
Mediterranean
As you sail the crystal-clear waters of the Mediterranean, watch as your ship glides past the sun-kissed shores of the Amalfi Coast, the ancient ruins of Rhodes, the whitewashed buildings of Mykonos, and the charming harbors of Croatia, each with its own story to tell. The vibrant hues of the sea and sky make every moment feel like a painting come to life.
Discover the Timeless Mediterranean
Set sail on an unforgettable Mediterranean cruise and explore iconic destinations rich in history, culture, and beauty. From the sun-drenched beaches of Santorini to the ancient streets of Rome, each port offers its own unique experience.
Discover the charm of Barcelona, wander the cobbled streets of Venice, or unwind along the Amalfi Coast’s stunning cliffs. Explore the historic ruins of Pompeii, or enjoy local wines in Sicily’s rolling hills. The Mediterranean offers a perfect mix of adventure and relaxation, with picturesque destinations like Athens, Dubrovnik, and the stunning Croatian coastline.
Onboard, indulge in world-class dining and entertainment while soaking in breathtaking views. Whether you seek ancient ruins, vibrant culture, or a relaxing retreat, the Mediterranean awaits with something for every traveler.
Embark on the Mediterranean cruise of a lifetime and experience some of the world’s most beautiful and timeless locations.
Ports
Mediterranean
We found
2251 cruises
1 / 30
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Duration
7 nights
Date
1 Dec 2026
Ship
MSC Sinfonia
- Departure - Genoa, Italy
- 7 stops
- Arrival - Genoa, Italy
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1 / 32
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Duration
7 nights
Date
1 Dec 2026
Ship
MSC Euribia
- Departure - Naples, Italy
- 7 stops
- Arrival - Naples, Italy
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1 / 21
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Duration
7 nights
Date
2 Dec 2026
Ship
MSC Orchestra
- Departure - Istanbul, Turkey
- 6 stops
- Arrival - Istanbul, Turkey
Show all departures (5)
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1 / 32
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Duration
7 nights
Date
2 Dec 2026
Ship
MSC Euribia
- Departure - Palermo, Sicily
- 7 stops
- Arrival - Palermo, Sicily
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1 / 12
5 % off — 2 days left
Duration
19 nights
Date
2 Dec 2026
Ship
Sirena
- Departure - Civitavecchia (Rome), Italy
- 19 stops
- Arrival - Lisbon, Portugal
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 30
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Duration
7 nights
Date
3 Dec 2026
Ship
MSC Sinfonia
- Departure - Civitavecchia (Rome), Italy
- 7 stops
- Arrival - Civitavecchia (Rome), Italy
Show all departures (14)
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1 / 27
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Duration
18 nights
Date
3 Dec 2026
Ship
Arcadia
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
2 Available promotions:
Bonus Onboard Credit: Up to £500 to spend at sea, New In: All-Inclusive cruising from £45pp/pd
1 / 32
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Duration
7 nights
Date
5 Dec 2026
Ship
MSC Euribia
- Departure - Barcelona, Spain
- 7 stops
- Arrival - Barcelona, Spain
Show all departures (19)
2 Available promotions:
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1 / 21
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Duration
7 nights
Date
5 Dec 2026
Ship
MSC Orchestra
- Departure - Bari, Italy
- 6 stops
- Arrival - Bari, Italy
Show all departures (6)
2 Available promotions:
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1 / 20
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Duration
7 nights
Date
5 Dec 2026
Ship
MSC World Asia
- Departure - Marseille, France
- 7 stops
- Arrival - Marseille, France
Show all departures (18)
Available promotion:
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1 / 17
6 % off — 2 days left
Duration
7 nights
Date
5 Dec 2026
Ship
Azamara Onward
- Departure - Civitavecchia (Rome), Italy
- 8 stops
- Arrival - Athens (Piraeus), Greece
Available promotion:
up to $750 Onboard Credit
1 / 30
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Duration
7 nights
Date
6 Dec 2026
Ship
MSC Sinfonia
- Departure - Barcelona, Spain
- 7 stops
- Arrival - Barcelona, Spain
Show all departures (13)
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1 / 32
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Duration
7 nights
Date
6 Dec 2026
Ship
MSC Euribia
- Departure - Marseille, France
- 7 stops
- Arrival - Marseille, France
Show all departures (20)
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1 / 15
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Duration
10 nights
Date
6 Dec 2026
Ship
MSC Lirica
- Departure - Split, Croatia
- 7 stops
- Arrival - Split, Croatia
Available promotion:
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1 / 20
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Duration
7 nights
Date
6 Dec 2026
Ship
MSC World Asia
- Departure - Genoa, Italy
- 7 stops
- Arrival - Genoa, Italy
Show all departures (18)
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1 / 24
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Duration
10 nights
Date
6 Dec 2026
Ship
MSC Magnifica
- Departure - Genoa, Italy
- 9 stops
- Arrival - Genoa, Italy
Show all departures (2)
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1 / 30
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Duration
7 nights
Date
7 Dec 2026
Ship
MSC Sinfonia
- Departure - Marseille, France
- 7 stops
- Arrival - Marseille, France
Show all departures (12)
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1 / 32
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Duration
7 nights
Date
7 Dec 2026
Ship
MSC Euribia
- Departure - Genoa, Italy
- 7 stops
- Arrival - Genoa, Italy
Show all departures (20)
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1 / 20
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Duration
7 nights
Date
7 Dec 2026
Ship
MSC World Asia
- Departure - Civitavecchia (Rome), Italy
- 7 stops
- Arrival - Civitavecchia (Rome), Italy
Show all departures (18)
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1 / 21
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Duration
7 nights
Date
7 Dec 2026
Ship
MSC Orchestra
- Departure - Athens (Piraeus), Greece
- 6 stops
- Arrival - Athens (Piraeus), Greece
Show all departures (7)
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1 / 24
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Duration
10 nights
Date
7 Dec 2026
Ship
MSC Magnifica
- Departure - Marseille, France
- 9 stops
- Arrival - Marseille, France
Show all departures (2)
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1 / 15
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Duration
10 nights
Date
7 Dec 2026
Ship
MSC Lirica
- Departure - Venice, Italy
- 7 stops
- Arrival - Venice, Italy
2 Available promotions:
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1 / 15
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Duration
10 nights
Date
7 Dec 2026
Ship
MSC Lirica
- Departure - Venice, Italy
- 7 stops
- Arrival - Venice, Italy
2 Available promotions:
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1 / 9
5 % off — 2 days left
Duration
14 nights
Date
7 Dec 2026
Ship
Seven Seas Navigator
- Departure - Barcelona, Spain
- 12 stops
- Arrival - Civitavecchia (Rome), Italy
1 / 24
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Duration
7 nights
Date
8 Dec 2026
Ship
MSC Magnifica
- Departure - Barcelona, Spain
- 6 stops
- Arrival - Civitavecchia (Rome), Italy
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1 / 24
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Duration
10 nights
Date
8 Dec 2026
Ship
MSC Magnifica
- Departure - Barcelona, Spain
- 9 stops
- Arrival - Barcelona, Spain
Available promotion:
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1 / 20
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Duration
7 nights
Date
8 Dec 2026
Ship
MSC World Asia
- Departure - Messina, Sicily
- 7 stops
- Arrival - Messina, Sicily
Show all departures (17)
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1 / 29
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Duration
12 nights
Date
8 Dec 2026
Ship
Celebrity Infinity
- Departure - Barcelona, Spain
- 9 stops
- Arrival - Barcelona, Spain
2 Available promotions:
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1 / 20
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Duration
3 nights
Date
11 Dec 2026
Ship
MSC World Asia
- Departure - Barcelona, Spain
- 4 stops
- Arrival - Civitavecchia (Rome), Italy
Available promotion:
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1 / 20
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Duration
7 nights
Date
11 Dec 2026
Ship
MSC World Asia
- Departure - Barcelona, Spain
- 7 stops
- Arrival - Barcelona, Spain
Show all departures (17)
2 Available promotions:
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1 / 30
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Duration
7 nights
Date
12 Dec 2026
Ship
MSC Sinfonia
- Departure - Valencia, Spain
- 7 stops
- Arrival - Valencia, Spain
Show all departures (14)
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1 / 24
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Duration
10 nights
Date
15 Dec 2026
Ship
MSC Magnifica
- Departure - Civitavecchia (Rome), Italy
- 9 stops
- Arrival - Civitavecchia (Rome), Italy
Available promotion:
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1 / 15
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Duration
11 nights
Date
16 Dec 2026
Ship
MSC Lirica
- Departure - Split, Croatia
- 9 stops
- Arrival - Split, Croatia
Show all departures (3)
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1 / 15
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Duration
11 nights
Date
17 Dec 2026
Ship
MSC Lirica
- Departure - Venice, Italy
- 9 stops
- Arrival - Venice, Italy
Show all departures (6)
2 Available promotions:
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1 / 15
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Duration
11 nights
Date
17 Dec 2026
Ship
MSC Lirica
- Departure - Venice, Italy
- 9 stops
- Arrival - Venice, Italy
2 Available promotions:
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1 / 31
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Duration
10 nights
Date
18 Dec 2026
Ship
Azura
- Departure - Santa Cruz, Tenerife
- 8 stops
- Arrival - Malaga, Spain
2 Available promotions:
Bonus Onboard Credit: Up to £290 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
1 / 31
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Duration
10 nights
Date
18 Dec 2026
Ship
Azura
- Departure - Santa Cruz, Tenerife
- 8 stops
- Arrival - Malaga, Spain
2 Available promotions:
Bonus Onboard Credit: Up to £290 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
1 / 31
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Duration
10 nights
Date
19 Dec 2026
Ship
Azura
- Departure - Santa Cruz, Tenerife
- 8 stops
- Arrival - Malaga, Spain
2 Available promotions:
Bonus Onboard Credit: Up to £290 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
1 / 31
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Duration
10 nights
Date
19 Dec 2026
Ship
Azura
- Departure - Santa Cruz, Tenerife
- 8 stops
- Arrival - Malaga, Spain
2 Available promotions:
Bonus Onboard Credit: Up to £290 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
1 / 26
5 % off — 2 days left
Duration
14 nights
Date
20 Dec 2026
Ship
Ambience
- Departure - Tilbury (London), Great Britain
- 9 stops
- Arrival - Tilbury (London), Great Britain
Available promotion:
FREE up to £800 Onboard Credit!
1 / 20
5 % off — 2 days left
Duration
15 nights
Date
21 Dec 2026
Ship
Ambition
- Departure - Tilbury (London), Great Britain
- 10 stops
- Arrival - Tilbury (London), Great Britain
Available promotion:
FREE up to £800 Onboard Credit!
1 / 12
5 % off — 2 days left
Duration
14 nights
Date
21 Dec 2026
Ship
Sirena
- Departure - Lisbon, Portugal
- 13 stops
- Arrival - Civitavecchia (Rome), Italy
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 9
5 % off — 2 days left
Duration
14 nights
Date
21 Dec 2026
Ship
Seven Seas Navigator
- Departure - Civitavecchia (Rome), Italy
- 12 stops
- Arrival - Athens (Piraeus), Greece
1 / 17
6 % off — 2 days left
Duration
7 nights
Date
22 Dec 2026
Ship
Azamara Onward
- Departure - Civitavecchia (Rome), Italy
- 7 stops
- Arrival - Barcelona, Spain
Available promotion:
up to $750 Onboard Credit
1 / 24
Discount — 2 days left
Duration
10 nights
Date
25 Dec 2026
Ship
MSC Magnifica
- Departure - Civitavecchia (Rome), Italy
- 9 stops
- Arrival - Civitavecchia (Rome), Italy
Available promotion:
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1 / 24
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Duration
10 nights
Date
26 Dec 2026
Ship
MSC Magnifica
- Departure - Genoa, Italy
- 9 stops
- Arrival - Genoa, Italy
Available promotion:
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1 / 24
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Duration
10 nights
Date
27 Dec 2026
Ship
MSC Magnifica
- Departure - Marseille, France
- 9 stops
- Arrival - Marseille, France
Available promotion:
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1 / 31
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Duration
11 nights
Date
28 Dec 2026
Ship
Azura
- Departure - Malaga, Spain
- 9 stops
- Arrival - Santa Cruz, Tenerife
2 Available promotions:
Bonus Onboard Credit: Up to £290 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
1 / 31
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Duration
11 nights
Date
28 Dec 2026
Ship
Azura
- Departure - Malaga, Spain
- 9 stops
- Arrival - Santa Cruz, Tenerife
2 Available promotions:
Bonus Onboard Credit: Up to £290 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
1 / 30
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Duration
7 nights
Date
28 Dec 2026
Ship
MSC Sinfonia
- Departure - Marseille, France
- 7 stops
- Arrival - Marseille, France
Available promotion:
Premium Drinks Package from £26pp/pn
50 of 2251 pcs