South America offers a diverse blend of vibrant cities, ancient ruins, and breathtaking natural wonders. From the lively streets of Rio de Janeiro to the historic ruins of Machu Picchu, this continent is full of life and adventure. Explore the Amazon Rainforest, the vast landscapes of Patagonia, and the dynamic cultures of Argentina, Brazil, and Peru. Whether you're seeking cultural immersion, outdoor adventure, or stunning landscapes, South America has something for every traveler.
South America
Discover the vibrant charm of South America's ports! From Rio's lively beaches to Buenos Aires' tango streets, embark on an unforgettable cruise adventure.
Ports
South America
We found
199 cruises
1 / 19
Discount — 3 days left
Duration
3 nights
Date
30 Nov 2026
Ship
MSC Musica
- Departure - Santos (São Paulo), Brazil
- 3 stops
- Arrival - Santos (São Paulo), Brazil
1 / 39
Duration
1 night
Date
1 Dec 2026
Ship
MSC Virtuosa
- Departure - Rio de Janeiro, Brazil
- 2 stops
- Arrival - Santos (São Paulo), Brazil
1 / 39
Discount — 3 days left
Duration
3 nights
Date
2 Dec 2026
Ship
MSC Virtuosa
- Departure - Santos (São Paulo), Brazil
- 3 stops
- Arrival - Santos (São Paulo), Brazil
1 / 33
Discount — 3 days left
Duration
3 nights
Date
2 Dec 2026
Ship
MSC Seaview
- Departure - Santos (São Paulo), Brazil
- 3 stops
- Arrival - Santos (São Paulo), Brazil
1 / 19
Discount — 3 days left
Duration
3 nights
Date
3 Dec 2026
Ship
MSC Musica
- Departure - Santos (São Paulo), Brazil
- 3 stops
- Arrival - Santos (São Paulo), Brazil
Show all departures (3)
1 / 29
Discount — 3 days left
Duration
3 nights
Date
3 Dec 2026
Ship
MSC Splendida
- Departure - Buenos Aires, Argentina
- 2 stops
- Arrival - Rio de Janeiro, Brazil
1 / 29
Discount — 3 days left
Duration
8 nights
Date
3 Dec 2026
Ship
MSC Splendida
- Departure - Buenos Aires, Argentina
- 6 stops
- Arrival - Buenos Aires, Argentina
Show all departures (8)
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 39
Discount — 3 days left
Duration
4 nights
Date
5 Dec 2026
Ship
MSC Virtuosa
- Departure - Santos (São Paulo), Brazil
- 4 stops
- Arrival - Maceió, Brazil
Show all departures (2)
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 39
Discount — 3 days left
Duration
3 nights
Date
5 Dec 2026
Ship
MSC Virtuosa
- Departure - Santos (São Paulo), Brazil
- 3 stops
- Arrival - Salvador de Bahia, Brazil
1 / 39
Discount — 3 days left
Duration
7 nights
Date
5 Dec 2026
Ship
MSC Virtuosa
- Departure - Santos (São Paulo), Brazil
- 5 stops
- Arrival - Santos (São Paulo), Brazil
Show all departures (16)
Available promotion:
Premium Drinks Package from £26pp/pn
10 of 199 pcs