South America offers a diverse blend of vibrant cities, ancient ruins, and breathtaking natural wonders. From the lively streets of Rio de Janeiro to the historic ruins of Machu Picchu, this continent is full of life and adventure. Explore the Amazon Rainforest, the vast landscapes of Patagonia, and the dynamic cultures of Argentina, Brazil, and Peru. Whether you're seeking cultural immersion, outdoor adventure, or stunning landscapes, South America has something for every traveler.
South America
Discover the vibrant charm of South America's ports! From Rio's lively beaches to Buenos Aires' tango streets, embark on an unforgettable cruise adventure.
Ports
South America
We found
198 cruises
1 / 39
Duration
1 night
Date
1 Dec 2026
Ship
MSC Virtuosa
- Departure - Rio de Janeiro, Brazil
- 2 stops
- Arrival - Santos (São Paulo), Brazil
1 / 39
Discount — 2 days left
Duration
3 nights
Date
2 Dec 2026
Ship
MSC Virtuosa
- Departure - Santos (São Paulo), Brazil
- 3 stops
- Arrival - Santos (São Paulo), Brazil
1 / 33
Discount — 2 days left
Duration
3 nights
Date
2 Dec 2026
Ship
MSC Seaview
- Departure - Santos (São Paulo), Brazil
- 3 stops
- Arrival - Santos (São Paulo), Brazil
1 / 19
Discount — 2 days left
Duration
3 nights
Date
3 Dec 2026
Ship
MSC Musica
- Departure - Santos (São Paulo), Brazil
- 3 stops
- Arrival - Santos (São Paulo), Brazil
Show all departures (3)
1 / 29
Discount — 2 days left
Duration
3 nights
Date
3 Dec 2026
Ship
MSC Splendida
- Departure - Buenos Aires, Argentina
- 2 stops
- Arrival - Rio de Janeiro, Brazil
1 / 29
Discount — 2 days left
Duration
8 nights
Date
3 Dec 2026
Ship
MSC Splendida
- Departure - Buenos Aires, Argentina
- 6 stops
- Arrival - Buenos Aires, Argentina
Show all departures (8)
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 39
Discount — 2 days left
Duration
4 nights
Date
5 Dec 2026
Ship
MSC Virtuosa
- Departure - Santos (São Paulo), Brazil
- 4 stops
- Arrival - Maceió, Brazil
Show all departures (2)
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 39
Discount — 2 days left
Duration
3 nights
Date
5 Dec 2026
Ship
MSC Virtuosa
- Departure - Santos (São Paulo), Brazil
- 3 stops
- Arrival - Salvador de Bahia, Brazil
1 / 39
Discount — 2 days left
Duration
7 nights
Date
5 Dec 2026
Ship
MSC Virtuosa
- Departure - Santos (São Paulo), Brazil
- 5 stops
- Arrival - Santos (São Paulo), Brazil
Show all departures (16)
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 33
Discount — 2 days left
Duration
8 nights
Date
5 Dec 2026
Ship
MSC Seaview
- Departure - Santos (São Paulo), Brazil
- 6 stops
- Arrival - Santos (São Paulo), Brazil
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 33
Discount — 2 days left
Duration
5 nights
Date
5 Dec 2026
Ship
MSC Seaview
- Departure - Santos (São Paulo), Brazil
- 5 stops
- Arrival - Buenos Aires, Argentina
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 17
Discount — 2 days left
Duration
14 nights
Date
5 Dec 2026
Ship
Celebrity Equinox
- Departure - Buenos Aires, Argentina
- 10 stops
- Arrival - Buenos Aires, Argentina
Show all departures (3)
2 Available promotions:
Black Friday Preview Sale: up to $700 OBC, Up to 75% off Second Guest
1 / 19
Discount — 2 days left
Duration
4 nights
Date
6 Dec 2026
Ship
MSC Musica
- Departure - Santos (São Paulo), Brazil
- 4 stops
- Arrival - Santos (São Paulo), Brazil
Show all departures (2)
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 33
Discount — 2 days left
Duration
8 nights
Date
6 Dec 2026
Ship
MSC Seaview
- Departure - Camboriu, Brazil
- 6 stops
- Arrival - Camboriu, Brazil
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 29
Discount — 2 days left
Duration
8 nights
Date
6 Dec 2026
Ship
MSC Splendida
- Departure - Rio de Janeiro, Brazil
- 6 stops
- Arrival - Rio de Janeiro, Brazil
Show all departures (6)
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 23
Discount — 2 days left
Duration
15 nights
Date
7 Dec 2026
Ship
Majestic Princess
- Departure - Buenos Aires, Argentina
- 10 stops
- Arrival - Valparaiso, Chile
Available promotion:
All-In: Upgrade to 'Princess Plus' for £53pp/pd
1 / 39
Discount — 2 days left
Duration
7 nights
Date
8 Dec 2026
Ship
MSC Virtuosa
- Departure - Salvador de Bahia, Brazil
- 5 stops
- Arrival - Salvador de Bahia, Brazil
Show all departures (15)
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 39
Discount — 2 days left
Duration
7 nights
Date
9 Dec 2026
Ship
MSC Virtuosa
- Departure - Maceió, Brazil
- 5 stops
- Arrival - Maceió, Brazil
Show all departures (14)
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 33
Discount — 2 days left
Duration
7 nights
Date
10 Dec 2026
Ship
MSC Seaview
- Departure - Buenos Aires, Argentina
- 5 stops
- Arrival - Buenos Aires, Argentina
Show all departures (9)
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 19
Discount — 2 days left
Duration
4 nights
Date
13 Dec 2026
Ship
MSC Musica
- Departure - Santos (São Paulo), Brazil
- 4 stops
- Arrival - Santos (São Paulo), Brazil
Show all departures (2)
Available promotion:
Premium Drinks Package from £26pp/pn
20 of 198 pcs