The Panama Canal offers a unique journey through one of the world’s greatest engineering marvels. Navigate through lush jungles, expansive lakes, and towering locks as you traverse the iconic waterway that connects the Atlantic and Pacific Oceans. Along the way, explore vibrant ports in Panama City, experience the rich history of the canal, and witness wildlife in the surrounding tropical landscapes. A cruise through the Panama Canal is a once-in-a-lifetime experience, filled with awe and adventure.
Panama Canal
Discover the wonders of the Panama Canal! Sail through this engineering marvel and explore vibrant ports filled with culture, history, and stunning landscapes.
Ports
Panama Canal
We found
143 cruises
1 / 20
Discount — 4 days left
Duration
16 nights
Date
3 Dec 2026
Ship
Crown Princess
- Departure - Los Angeles, USA
- 9 stops
- Arrival - Fort Lauderdale, Florida
Available promotion:
All-In: Upgrade to 'Princess Plus' for £53pp/pd
1 / 12
5 % off — 4 days left
Duration
15 nights
Date
19 Dec 2026
Ship
Insignia
- Departure - Miami, Florida, USA
- 11 stops
- Arrival - Callao (Lima), Peru
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 9
5 % off — 4 days left
Duration
16 nights
Date
29 Dec 2026
Ship
Seven Seas Grandeur
- Departure - Miami, Florida, USA
- 9 stops
- Arrival - Los Angeles, USA
1 / 26
Discount — 4 days left
Duration
26 nights
Date
10 Jan 2027
Ship
Queen Victoria
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Los Angeles, USA
4 Available promotions:
30% off Signature Packages!, Black Friday Event: 10% off!, Get up to $800 Onboard Credit, Save 10% off your Drinks Package
1 / 9
5 % off — 4 days left
Duration
14 nights
Date
12 Jan 2027
Ship
Seven Seas Splendor
- Departure - Miami, Florida, USA
- 11 stops
- Arrival - Panama City, Panama
1 / 9
5 % off — 4 days left
Duration
42 nights
Date
12 Jan 2027
Ship
Seven Seas Splendor
- Departure - Miami, Florida, USA
- 25 stops
- Arrival - Papeete (Tahiti), French Polynesia
1 / 35
Discount — 4 days left
Duration
56 nights
Date
22 Jan 2027
Ship
Queen Anne
- Departure - Fort Lauderdale, Florida
- 30 stops
- Arrival - Fort Lauderdale, Florida
3 Available promotions:
30% off Signature Packages!, Get up to $800 Onboard Credit, Save 10% off your Drinks Package
1 / 35
Discount — 4 days left
Duration
56 nights
Date
22 Jan 2027
Ship
Queen Anne
- Departure - Fort Lauderdale, Florida
- 30 stops
- Arrival - Fort Lauderdale, Florida
3 Available promotions:
30% off Signature Packages!, Get up to $800 Onboard Credit, Save 10% off your Drinks Package
1 / 9
5 % off — 4 days left
Duration
16 nights
Date
24 Jan 2027
Ship
Seven Seas Grandeur
- Departure - Los Angeles, USA
- 8 stops
- Arrival - Miami, Florida, USA
1 / 14
Discount — 4 days left
Duration
16 nights
Date
29 Jan 2027
Ship
Island Princess
- Departure - San Diego, USA
- 9 stops
- Arrival - Fort Lauderdale, Florida
Available promotion:
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1 / 15
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Duration
16 nights
Date
13 Feb 2027
Ship
Norwegian Star
- Departure - San Diego, USA
- 10 stops
- Arrival - Miami, Florida, USA
Available promotion:
Upgrade to "Free At Sea" from £99pp
1 / 14
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Duration
16 nights
Date
14 Feb 2027
Ship
Island Princess
- Departure - Fort Lauderdale, Florida
- 9 stops
- Arrival - Los Angeles, USA
Available promotion:
All-In: Upgrade to 'Princess Plus' for £53pp/pd
1 / 18
5 % off — 4 days left
Duration
20 nights
Date
19 Feb 2027
Ship
Allura
- Departure - San Juan, Puerto Rico
- 15 stops
- Arrival - Miami, Florida, USA
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 17
5 % off — 4 days left
Duration
11 nights
Date
22 Feb 2027
Ship
Seven Seas Prestige
- Departure - Panama City, Panama
- 9 stops
- Arrival - Miami, Florida, USA
1 / 9
5 % off — 4 days left
Duration
14 nights
Date
23 Feb 2027
Ship
Seven Seas Grandeur
- Departure - Miami, Florida, USA
- 11 stops
- Arrival - Panama City, Panama
1 / 18
5 % off — 4 days left
Duration
12 nights
Date
27 Feb 2027
Ship
Allura
- Departure - Miami, Florida, USA
- 9 stops
- Arrival - Miami, Florida, USA
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 35
Discount — 4 days left
Duration
19 nights
Date
28 Feb 2027
Ship
Queen Anne
- Departure - Valparaiso, Chile
- 11 stops
- Arrival - Fort Lauderdale, Florida
4 Available promotions:
30% off Signature Packages!, Black Friday Event: 10% off!, Get up to $800 Onboard Credit, Save 10% off your Drinks Package
1 / 35
Discount — 4 days left
Duration
19 nights
Date
28 Feb 2027
Ship
Queen Anne
- Departure - Valparaiso, Chile
- 11 stops
- Arrival - Fort Lauderdale, Florida
4 Available promotions:
30% off Signature Packages!, Black Friday Event: 10% off!, Get up to $800 Onboard Credit, Save 10% off your Drinks Package
1 / 14
Discount — 4 days left
Duration
16 nights
Date
2 Mar 2027
Ship
Island Princess
- Departure - Los Angeles, USA
- 9 stops
- Arrival - Fort Lauderdale, Florida
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £175pp!
1 / 17
5 % off — 4 days left
Duration
10 nights
Date
5 Mar 2027
Ship
Marina
- Departure - Miami, Florida, USA
- 10 stops
- Arrival - Panama City, Panama
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 17
5 % off — 4 days left
Duration
20 nights
Date
5 Mar 2027
Ship
Marina
- Departure - Miami, Florida, USA
- 19 stops
- Arrival - Miami, Florida, USA
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 9
5 % off — 4 days left
Duration
22 nights
Date
9 Mar 2027
Ship
Seven Seas Grandeur
- Departure - Panama City, Panama
- 10 stops
- Arrival - Panama City, Panama
Available promotion:
Black Friday Early Access: up to 40% off & US$500 Onboard Credit
1 / 10
5 % off — 4 days left
Duration
16 nights
Date
10 Mar 2027
Ship
Seven Seas Mariner
- Departure - Callao (Lima), Peru
- 13 stops
- Arrival - Miami, Florida, USA
1 / 17
5 % off — 4 days left
Duration
10 nights
Date
15 Mar 2027
Ship
Marina
- Departure - Panama City, Panama
- 10 stops
- Arrival - Miami, Florida, USA
2 Available promotions:
Black Friday Event: 10% off!, Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 14
Discount — 4 days left
Duration
16 nights
Date
18 Mar 2027
Ship
Island Princess
- Departure - Fort Lauderdale, Florida
- 9 stops
- Arrival - Los Angeles, USA
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £175pp!
1 / 14
6 % off — 4 days left
Duration
11 nights
Date
18 Mar 2027
Ship
Azamara Journey
- Departure - Callao (Lima), Peru
- 7 stops
- Arrival - Miami, Florida, USA
Available promotion:
up to $750 Onboard Credit
1 / 26
6 % off — 4 days left
Duration
16 nights
Date
26 Mar 2027
Ship
Brilliant Lady
- Departure - Miami, Florida, USA
- 8 stops
- Arrival - Los Angeles, USA
Show all departures (2)
Available promotion:
Black Friday Preview: 80% off your second sailor + up to in $600 FREE drinks!
1 / 29
Discount — 4 days left
Duration
29 nights
Date
28 Mar 2027
Ship
MSC Poesia
- Departure - Miami, Florida, USA
- 17 stops
- Arrival - Seattle, USA
Available promotion:
Black Friday: up to 30% Savings!
1 / 17
Duration
16 nights
Date
29 Mar 2027
Ship
Carnival Spirit
- Departure - Mobile (Alabama), USA
- 6 stops
- Arrival - Seattle, USA
Show all departures (2)
1 / 9
5 % off — 4 days left
Duration
14 nights
Date
31 Mar 2027
Ship
Seven Seas Grandeur
- Departure - Panama City, Panama
- 12 stops
- Arrival - Miami, Florida, USA
1 / 25
Discount — 4 days left
Duration
16 nights
Date
3 Apr 2027
Ship
Star Princess
- Departure - Fort Lauderdale, Florida
- 7 stops
- Arrival - Los Angeles, USA
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £58pp/pd, Blue Friday Sale: Save up to £175pp!
1 / 14
Discount — 4 days left
Duration
16 nights
Date
3 Apr 2027
Ship
Island Princess
- Departure - Los Angeles, USA
- 9 stops
- Arrival - Fort Lauderdale, Florida
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £175pp!
1 / 19
Duration
16 nights
Date
4 Apr 2027
Ship
Carnival Legend
- Departure - Tampa, FL USA
- 7 stops
- Arrival - Seattle, USA
1 / 20
Discount — 4 days left
Duration
16 nights
Date
4 Apr 2027
Ship
Crown Princess
- Departure - Fort Lauderdale, Florida
- 9 stops
- Arrival - Los Angeles, USA
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £175pp!
1 / 29
Discount — 4 days left
Duration
18 nights
Date
8 Apr 2027
Ship
MSC Poesia
- Departure - Miami, Florida, USA
- 9 stops
- Arrival - Seattle, USA
2 Available promotions:
Black Friday: up to 30% Savings!, Premium Drinks Package from £26pp/pn
1 / 29
Discount — 4 days left
Duration
25 nights
Date
8 Apr 2027
Ship
MSC Poesia
- Departure - Miami, Florida, USA
- 15 stops
- Arrival - Seattle, USA
2 Available promotions:
Black Friday: up to 30% Savings!, Premium Drinks Package from £26pp/pn
1 / 29
Discount — 4 days left
Duration
19 nights
Date
9 Apr 2027
Ship
Norwegian Bliss
- Departure - New York, USA
- 11 stops
- Arrival - San Francisco, USA
Available promotion:
Upgrade to "Free At Sea" from £99pp
1 / 29
Discount — 4 days left
Duration
22 nights
Date
9 Apr 2027
Ship
Norwegian Bliss
- Departure - New York, USA
- 13 stops
- Arrival - Seattle, USA
Available promotion:
Upgrade to "Free At Sea" from £99pp
1 / 17
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Duration
15 nights
Date
18 Apr 2027
Ship
Celebrity Summit
- Departure - Tampa, FL USA
- 8 stops
- Arrival - Los Angeles, USA
2 Available promotions:
Black Friday Preview Sale: up to $700 OBC, Up to 75% off Second Guest
1 / 14
Discount — 4 days left
Duration
16 nights
Date
19 Apr 2027
Ship
Island Princess
- Departure - Fort Lauderdale, Florida
- 9 stops
- Arrival - Los Angeles, USA
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £175pp!
1 / 19
Discount — 4 days left
Duration
15 nights
Date
21 Apr 2027
Ship
Norwegian Joy
- Departure - Miami, Florida, USA
- 9 stops
- Arrival - Los Angeles, USA
Show all departures (2)
Available promotion:
Upgrade to "Free At Sea" from £99pp
1 / 14
6 % off — 4 days left
Duration
17 nights
Date
24 May 2027
Ship
Azamara Quest
- Departure - San Diego, USA
- 10 stops
- Arrival - Miami, Florida, USA
Available promotion:
up to $750 Onboard Credit
1 / 17
Discount — 4 days left
Duration
18 nights
Date
18 Sep 2027
Ship
Celebrity Summit
- Departure - Los Angeles, USA
- 8 stops
- Arrival - Boston, USA
2 Available promotions:
Black Friday Preview Sale: up to $700 OBC, Up to 75% off Second Guest
1 / 14
Discount — 4 days left
Duration
23 nights
Date
22 Sep 2027
Ship
Coral Princess
- Departure - Vancouver, Canada
- 11 stops
- Arrival - New York, USA
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £300pp!
1 / 17
Duration
16 nights
Date
25 Sep 2027
Ship
Carnival Spirit
- Departure - Seattle, USA
- 6 stops
- Arrival - Galveston, Texas, USA
1 / 14
Discount — 4 days left
Duration
18 nights
Date
27 Sep 2027
Ship
Coral Princess
- Departure - Los Angeles, USA
- 9 stops
- Arrival - New York, USA
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £300pp!
1 / 29
Discount — 4 days left
Duration
19 nights
Date
27 Sep 2027
Ship
MSC Poesia
- Departure - Seattle, USA
- 9 stops
- Arrival - Miami, Florida, USA
Available promotion:
Premium Drinks Package from £26pp/pn
1 / 19
Discount — 4 days left
Duration
17 nights
Date
30 Sep 2027
Ship
Norwegian Joy
- Departure - Los Angeles, USA
- 11 stops
- Arrival - Miami, Florida, USA
Available promotion:
Upgrade to "Free At Sea" from £99pp
1 / 25
Discount — 4 days left
Duration
23 nights
Date
3 Oct 2027
Ship
Star Princess
- Departure - Vancouver, Canada
- 12 stops
- Arrival - Port Canaveral (Orlando), USA
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £58pp/pd, Blue Friday Sale: Save up to £300pp!
1 / 14
Discount — 4 days left
Duration
23 nights
Date
6 Oct 2027
Ship
Island Princess
- Departure - Vancouver, Canada
- 14 stops
- Arrival - Fort Lauderdale, Florida
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £300pp!
1 / 25
Discount — 4 days left
Duration
16 nights
Date
10 Oct 2027
Ship
Star Princess
- Departure - Los Angeles, USA
- 7 stops
- Arrival - Port Canaveral (Orlando), USA
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £58pp/pd, Blue Friday Sale: Save up to £175pp!
1 / 26
5 % off — 4 days left
Duration
32 nights
Date
10 Oct 2027
Ship
Vista
- Departure - Montreal, Canada
- 21 stops
- Arrival - Los Angeles, USA
2 Available promotions:
Black Friday: up to 50% Savings, Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 14
Discount — 4 days left
Duration
16 nights
Date
13 Oct 2027
Ship
Island Princess
- Departure - Los Angeles, USA
- 9 stops
- Arrival - Fort Lauderdale, Florida
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £175pp!
1 / 29
Discount — 4 days left
Duration
17 nights
Date
19 Oct 2027
Ship
Norwegian Bliss
- Departure - Los Angeles, USA
- 11 stops
- Arrival - Miami, Florida, USA
Available promotion:
Upgrade to "Free At Sea" from £99pp
1 / 29
Discount — 4 days left
Duration
20 nights
Date
19 Oct 2027
Ship
Norwegian Bliss
- Departure - Los Angeles, USA
- 12 stops
- Arrival - New York, USA
Available promotion:
Upgrade to "Free At Sea" from £99pp
1 / 21
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Duration
16 nights
Date
24 Oct 2027
Ship
Emerald Princess
- Departure - Los Angeles, USA
- 9 stops
- Arrival - Fort Lauderdale, Florida
3 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Black Friday Event: 10% off!, Blue Friday Sale: Save up to £175pp!
1 / 26
5 % off — 4 days left
Duration
18 nights
Date
24 Oct 2027
Ship
Vista
- Departure - Miami, Florida, USA
- 11 stops
- Arrival - Los Angeles, USA
3 Available promotions:
Black Friday Event: 10% off!, Black Friday: up to 50% Savings, Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 9
5 % off — 4 days left
Duration
14 nights
Date
4 Nov 2027
Ship
Seven Seas Grandeur
- Departure - New York, USA
- 8 stops
- Arrival - Miami, Florida, USA
1 / 26
6 % off — 4 days left
Duration
17 nights
Date
27 Nov 2027
Ship
Brilliant Lady
- Departure - Los Angeles, USA
- 9 stops
- Arrival - Miami, Florida, USA
Available promotion:
Black Friday Preview: 80% off your second sailor + up to in $600 FREE drinks!
1 / 13
5 % off — 4 days left
Duration
29 nights
Date
6 Dec 2027
Ship
Sonata
- Departure - Miami, Florida, USA
- 19 stops
- Arrival - Los Angeles, USA
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 14
Discount — 4 days left
Duration
16 nights
Date
13 Dec 2027
Ship
Island Princess
- Departure - Fort Lauderdale, Florida
- 9 stops
- Arrival - Los Angeles, USA
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £175pp!
1 / 13
5 % off — 4 days left
Duration
16 nights
Date
19 Dec 2027
Ship
Sonata
- Departure - Miami, Florida, USA
- 10 stops
- Arrival - Los Angeles, USA
2 Available promotions:
Black Friday: up to 50% Savings, Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 9
5 % off — 4 days left
Duration
16 nights
Date
20 Dec 2027
Ship
Seven Seas Splendor
- Departure - Miami, Florida, USA
- 8 stops
- Arrival - San Francisco, USA
1 / 14
6 % off — 4 days left
Duration
28 nights
Date
27 Dec 2027
Ship
Azamara Quest
- Departure - Bridgetown, Barbados
- 21 stops
- Arrival - Valparaiso, Chile
Available promotion:
up to $750 Onboard Credit
1 / 14
Discount — 4 days left
Duration
16 nights
Date
29 Dec 2027
Ship
Island Princess
- Departure - Los Angeles, USA
- 9 stops
- Arrival - Fort Lauderdale, Florida
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £175pp!
1 / 14
Discount — 4 days left
Duration
15 nights
Date
3 Jan 2028
Ship
Coral Princess
- Departure - Fort Lauderdale, Florida
- 8 stops
- Arrival - Los Angeles, USA
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £175pp!
1 / 14
6 % off — 4 days left
Duration
9 nights
Date
5 Jan 2028
Ship
Azamara Quest
- Departure - Miami, Florida, USA
- 9 stops
- Arrival - Panama City, Panama
Available promotion:
up to $750 Onboard Credit
1 / 17
6 % off — 4 days left
Duration
14 nights
Date
5 Jan 2028
Ship
Azamara Onward
- Departure - Miami, Florida, USA
- 11 stops
- Arrival - Callao (Lima), Peru
Available promotion:
up to $750 Onboard Credit
1 / 12
5 % off — 4 days left
Duration
14 nights
Date
5 Jan 2028
Ship
Sirena
- Departure - Miami, Florida, USA
- 11 stops
- Arrival - Callao (Lima), Peru
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 14
6 % off — 4 days left
Duration
19 nights
Date
5 Jan 2028
Ship
Azamara Quest
- Departure - Miami, Florida, USA
- 15 stops
- Arrival - Valparaiso, Chile
Available promotion:
up to $750 Onboard Credit
1 / 12
5 % off — 4 days left
Duration
65 nights
Date
5 Jan 2028
Ship
Sirena
- Departure - Miami, Florida, USA
- 40 stops
- Arrival - Miami, Florida, USA
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 17
5 % off — 4 days left
Duration
10 nights
Date
6 Jan 2028
Ship
Marina
- Departure - Miami, Florida, USA
- 9 stops
- Arrival - Panama City, Panama
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 17
5 % off — 4 days left
Duration
20 nights
Date
6 Jan 2028
Ship
Marina
- Departure - Miami, Florida, USA
- 16 stops
- Arrival - Miami, Florida, USA
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 13
5 % off — 4 days left
Duration
16 nights
Date
6 Jan 2028
Ship
Sonata
- Departure - Los Angeles, USA
- 10 stops
- Arrival - Miami, Florida, USA
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 13
5 % off — 4 days left
Duration
44 nights
Date
6 Jan 2028
Ship
Sonata
- Departure - Los Angeles, USA
- 27 stops
- Arrival - Miami, Florida, USA
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
1 / 35
Discount — 4 days left
Duration
15 nights
Date
9 Jan 2028
Ship
Norwegian Encore
- Departure - Los Angeles, USA
- 9 stops
- Arrival - Miami, Florida, USA
Available promotion:
Upgrade to "Free At Sea" from £99pp
1 / 35
Discount — 4 days left
Duration
27 nights
Date
11 Jan 2028
Ship
Queen Anne
- Departure - Southampton, Great Britain
- 10 stops
- Arrival - Los Angeles, USA
3 Available promotions:
30% off Signature Packages!, Get up to $800 Onboard Credit, Save 10% off your Drinks Package
1 / 10
5 % off — 4 days left
Duration
14 nights
Date
13 Jan 2028
Ship
Seven Seas Voyager
- Departure - Miami, Florida, USA
- 10 stops
- Arrival - Callao (Lima), Peru
1 / 14
Discount — 4 days left
Duration
16 nights
Date
14 Jan 2028
Ship
Island Princess
- Departure - Fort Lauderdale, Florida
- 9 stops
- Arrival - Los Angeles, USA
2 Available promotions:
All-In: Upgrade to 'Princess Plus' for £53pp/pd, Blue Friday Sale: Save up to £175pp!
1 / 17
5 % off — 4 days left
Duration
10 nights
Date
16 Jan 2028
Ship
Marina
- Departure - Panama City, Panama
- 8 stops
- Arrival - Miami, Florida, USA
Available promotion:
Your World Included™ - Choice of Complimentary Wine & Beer or Shore Excursion Credit
80 of 143 pcs