Puerto Ayora (Santa Cruz Island)

Puerto Ayora (Santa Cruz Island)

Discover the vibrant charm of Puerto Ayora on Santa Cruz Island, where adventure meets relaxation. Dive into the heart of the Galápagos with us!

Nestled in the heart of the Galápagos Islands, Puerto Ayora on Santa Cruz Island is your gateway to an unforgettable adventure. This vibrant port town is a bustling hub of activity, offering a perfect blend of natural beauty and modern amenities. As you stroll along the picturesque waterfront, you'll find charming cafes, local markets, and a lively atmosphere that captures the essence of island life. Cruising to and from Puerto Ayora is a dream come true for nature enthusiasts and explorers alike. The surrounding waters are teeming with unique wildlife, from playful sea lions to majestic sea turtles, making every voyage an extraordinary experience. Whether you're embarking on a cruise to explore the enchanting islands or returning to the comfort of Puerto Ayora, this port promises a seamless blend of relaxation and adventure, ensuring your holiday is nothing short of spectacular.

Santa Cruz

We found

201 cruises

Azura, Canary Islands
1 / 31
Discount — 3 days left
P&O Cruises
Duration
7 nights
Date
4 Dec 2026
Ship
Azura
  • Departure - Santa Cruz, Tenerife
  • 6 stops  
  • Arrival - Santa Cruz, Tenerife
£499
From
£480
Price per person / inside stateroom
Show all departures (10)
2 Available promotions:
Bonus Onboard Credit: Up to £230 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
Azura, Canary Islands
1 / 31
Discount — 3 days left
P&O Cruises
Duration
7 nights
Date
4 Dec 2026
Ship
Azura
  • Departure - Santa Cruz, Tenerife
  • 6 stops  
  • Arrival - Santa Cruz, Tenerife
£499
From
£480
Price per person / inside stateroom
Show all departures (10)
2 Available promotions:
Bonus Onboard Credit: Up to £230 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
Azura, Canary Islands
1 / 31
Discount — 3 days left
P&O Cruises
Duration
14 nights
Date
4 Dec 2026
Ship
Azura
  • Departure - Santa Cruz, Tenerife
  • 11 stops  
  • Arrival - Santa Cruz, Tenerife
£899
From
£864
Price per person / inside stateroom
Show all departures (3)
2 Available promotions:
Bonus Onboard Credit: Up to £440 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
Azura, Canary Islands
1 / 31
Discount — 3 days left
P&O Cruises
Duration
14 nights
Date
4 Dec 2026
Ship
Azura
  • Departure - Santa Cruz, Tenerife
  • 11 stops  
  • Arrival - Santa Cruz, Tenerife
£899
From
£864
Price per person / inside stateroom
Show all departures (3)
2 Available promotions:
Bonus Onboard Credit: Up to £440 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
Azura, Canary Islands
1 / 31
Discount — 3 days left
P&O Cruises
Duration
7 nights
Date
5 Dec 2026
Ship
Azura
  • Departure - Santa Cruz, Tenerife
  • 6 stops  
  • Arrival - Santa Cruz, Tenerife
£499
From
£480
Price per person / inside stateroom
Show all departures (9)
2 Available promotions:
Bonus Onboard Credit: Up to £230 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
Azura, Canary Islands
1 / 31
Discount — 3 days left
P&O Cruises
Duration
7 nights
Date
5 Dec 2026
Ship
Azura
  • Departure - Santa Cruz, Tenerife
  • 6 stops  
  • Arrival - Santa Cruz, Tenerife
£499
From
£480
Price per person / inside stateroom
Show all departures (9)
2 Available promotions:
Bonus Onboard Credit: Up to £230 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
Azura, Canary Islands
1 / 31
Discount — 3 days left
P&O Cruises
Duration
14 nights
Date
5 Dec 2026
Ship
Azura
  • Departure - Santa Cruz, Tenerife
  • 11 stops  
  • Arrival - Santa Cruz, Tenerife
£799
From
£768
Price per person / inside stateroom
Show all departures (3)
2 Available promotions:
Bonus Onboard Credit: Up to £440 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
Azura, Canary Islands
1 / 31
Discount — 3 days left
P&O Cruises
Duration
14 nights
Date
5 Dec 2026
Ship
Azura
  • Departure - Santa Cruz, Tenerife
  • 11 stops  
  • Arrival - Santa Cruz, Tenerife
£799
From
£768
Price per person / inside stateroom
Show all departures (3)
2 Available promotions:
Bonus Onboard Credit: Up to £440 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
Azura, Canary Islands
1 / 31
Discount — 3 days left
P&O Cruises
Duration
7 nights
Date
11 Dec 2026
Ship
Azura
  • Departure - Santa Cruz, Tenerife
  • 6 stops  
  • Arrival - Santa Cruz, Tenerife
£499
From
£480
Price per person / inside stateroom
Show all departures (4)
2 Available promotions:
Bonus Onboard Credit: Up to £230 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
Azura, Canary Islands
1 / 31
Discount — 3 days left
P&O Cruises
Duration
7 nights
Date
11 Dec 2026
Ship
Azura
  • Departure - Santa Cruz, Tenerife
  • 6 stops  
  • Arrival - Santa Cruz, Tenerife
£499
From
£480
Price per person / inside stateroom
Show all departures (4)
2 Available promotions:
Bonus Onboard Credit: Up to £230 to spend at sea, New In: All-Inclusive cruising from £49pp/pd
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